Zainab AJ AL-Mashhadi
Department of Oral Diagnosis, College of Dentistry, University of Baghdad, IraqPublications
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Research Article
Local Evaluation of Chitosan and B-Tricalcium Phosphate Alone and Combination in Bone Defect of Rabbit by Histological and Histomorphometric Analysis
Author(s): Zainab AJ AL-Mashhadi* and Nada MH AL-Ghaban
Background: Repair of bone tissue is a complex multistep process including proliferation, migration, activation, and differentiation of many type of cells, guided toward the mineralization and remodelling of the defect site. Chitosan and beta-tricalcium phosphate may help to increase the bone minerals contents, mechanical strength and density of bone. Objectives: The aim of this research was to evaluate the process of bone regeneration in rabbits after surgical osteotomy by using chitosan and beta-tricalcium phosphate separately or in combination of chitosan/beta-tricalcium phosphate. Materials and Methods: A total of 32 New Zealand rabbits with average weight of 1.5-2 kg were used in this study. Animals were randomly divided into four groups (8 rabbits for each). Intrabony defect of about 3 mm width and 3 mm depth wer.. Read More»