Tanuja Lella
Dr, Department of Pharmacology, Sree Balaji Medical College and Hospital, Chennai, Tamilnadu, IndiaPublications
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Research Article
Comparative Study of Costus Igneus and Metformin in In-Vitro Inhibitory Activity of α-Amylase and α-Glucosidase Activity
Author(s): Sanjana V, Tanuja Lella*, Arul Amutha Elizabeth, Roshni AS, Brigida S and Vishnupriya G
The objective of the present study was to compare the α-amylase and α-glucosidase inhibition activity of aqueous extracts of costus igneus with that of metformin in in-vitro studies. Different concentrations of the aqueous extract of the leaf from the plant costus igneus and the solution of drug metformin (100-500 μl) and standard drug (Acarbose) were taken and assessed for the antidibetic activity based on their α-amylase and α-glucosidase inhibition. The alpha-amylase inhibition action of Costus igneus was 89% of that of metformin at a concentration of 500 μg. The alpha-glucosidase inhibition action of Costus igneus was 66.6% of that of metformin at a concentration of 500 μg. The study has shown good results and could be a potential topic for exploration of antidiabetic properties. The aqueous extract of the leaves of Costus.. Read More»