Senol Dane
Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, Nile University of Nigeria, Abuja, NigeriaPublications
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Research
Evaluating the Effects of Administration of the Ethanolic Leaf Extracts of Jatropha curcas and Ascorbic Acid on the Male Reproductive Functions in Alloxan-Induced Diabetic Rats
Author(s): Akin Olanipekun, John Ogedengbe, Olorunshola Kolawole and Senol Dane*
Introduction: The focus of this study is to compare the androgenic, antioxidant, and antidiabetic properties of ethanolic leaf extract of Jatrophas curcas when co-administered with ascorbic acid to when administered separately in alloxan-induced diabetic rats. Method: 48 adult male Wistar rats were divided into 8 groups. Group I: Normal control rats, Group II, Group III, Group IV were normal rats fed with Jatropha curcas (500mg/kg/d), Ascorbic acid (250mg/kg/d), and Jatropha curcas+ascorbic acid respectively. Diabetic rats were untreated in Group V, while diabetic rats in Groups VI, VII, and VIII were given Jatropha curcas (500mg/kg/day), ascorbic acid alone (250mg/kg/d), and Jatropha curcas+ascorbic acid, respectively. They were treated for 28 days, and the body weights and fasting blood glucose were checked weekly. The level of testicular antioxidant enzymes, sperm quality, and repr.. Read More»