Safa Ali Hamad
Department of Periodontics, College of Dentistry, University of Baghdad, IraqPublications
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Research
Assessment of Serum Levels of Soluble Urokinase Plasminogen Activator Receptor (suPAR) in Patients with Periodontitis and Atheroscletotic Cardiovascular Disease
Author(s): Safa Ali Hamad* and Maha Shukri Mahmood
Background: Soluble urokinase plasminogen activator receptor (suPAR) has been identified as a biomarker of inflammation and immune activation. SuPAR has been employed as a marker of inflammation in the assessment of patients with cardiac disorders in recent years, either alone or in conjunction with other biomarkers of inflammation. Earlier studies have shown that suPAR is involved in the homeostasis of leukocyte and endothelial cells and hence in coronary heart disease (CHD) and periodontitis development. Subjects, materials and methods: This study recruited 88 subjects, both sexes, ages ranged from 36 to 66 years old, and were arranged into 4 groups: group A, 25 patients with atherosclerotic cardiovascular disease (ASCVD) but no periodontal disease, group B, 25 patients with periodontitis but no systemic disease, group C, 25 patients with both ASCVD and periodontitis, and group D, 1.. Read More»