Reza Aghabozorgi
Department of Hematology and Medical Oncology, Arak University of Medical Sciences, Arak, IranPublications
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Research Article
Evaluation of eradication therapy for Helicobacter pylori on platelet counts of Patients with Immune thrombocytopenic purpura (ITP)
Author(s): Reza Aghabozorgi, Ali Arash Anoushirvani*, Hossein Jebali and Azim Froozan
Background: Immune thrombocytopenic purpura (ITP) is an acquired disorder that causes platelet degeneration by mediating immune responses and possibly inhibiting platelet release from megakaryocytes. The role of Helicobacter pylori in the development of ITP is not well-known, and there are many hypotheses about the mechanism for creating ITP due to Helicobacter pylori infection. Regarding the contradictory results of various studies, we decided to investigate the effect of Helicobacter pylori root cytotoxic treatment in ITP infected patients. Methods: This study was a clinical trial on 115 approved ITP patients. Stool antigen tests (SATs) were used to screening for H. pylori infection. Infected patients were treated with standard Helicobacter pylori regimens for 14 days and then followed for 6 mon.. Read More»