Maha SH Mahmood
Department of periodontics, College of dentistry, University of Baghdad, Baghdad, IraqPublications
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Research
Potential Antioxidant Effect of Systemic Melatonin Therapy on Obese Periodontitis Patient
Author(s): Hussam Sami Ismail* and Maha SH Mahmood
Background: Periodontitis and obesity are two common chronic inflammatory diseases leading to increased systemic inflammation, metabolic dysregulation and dyslipidemia, It has been reported that obesity may be associated to periodontitis through the increased production of reactive oxygen species (ROS).To address this aspect, the adjunctive use of melatonin as antioxidant, anti-inflammatory, immunomodulatory medication in order to improve periodontal condition associated with obesity. Aim of the study: To evaluate the effectiveness of adjunctive systemic administration of melatonin therapy to mechanical non- surgical periodontal therapy in periodontitis patients associated with obesity. Material and methods: Eighty subjects included in the study were divided into the following groups: Group I: 20 subjects with healthy periodontium and normal weight (contr.. Read More»