Hadeel Mazin Akram
Department of Periodontics, University of Baghdad, Baghdad, IraqPublications
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Research Article
Assessment of Salivary Macrophage Inflammatory Protein-1 Alpha Level in Different Stages of Periodontitis
Author(s): Riyam Muthanna Muhammed* and Hadeel Mazin Akram
Introduction: Microbial plaque causes initiation of periodontal diseases, and it induces an inflammatory host immune response. Macrophage Inflammatory Protein-1 alpha (MIP-1α) is a chemokine that is thought to have a role in periodontitis by activating osteoclasts and mediating T helper-1 cytokines that promote destruction of tissues. Aims: This study’s aim is to evaluate salivary levels of MIP-1α in different stages (I-III) of periodontitis in comparison to healthy controls and to correlate their levels with clinical periodontal parameters. Materials and methods: The sample population which consisted of (70) male and female participants was allocated into four groups: clinically healthy periodontium control group (n=10), stage I periodontitis group (n=20), stage II periodontitis group (n=20) and stage III periodontitis group (n=20). Co.. Read More»