Alaa Omran Ali Almosawi
College of Dentistry, University of Baghdad, IraqPublications
-
Research
Expression of Collagen 1 and Heat Shock Protein 47 in Hereditary Gingival Fibromatosis (Immunohistochemical Study)
Author(s): Alaa Omran Ali Almosawi
Background: The gingiva is part of the masticatory mucosa that acts as a barrier against mechanical stress and pathogen. It is made up of a dense, vascular fibrous tissue with a keratinized stratified squamous epithelium, surrounded by mucous membrane that is attached firmly to the periosteum of the alveolar processes of the maxilla and mandible. Gingival enlargement is one of most commonly presenting gingival disease. Clinically described as gingival enlargement or overgrowth. Gingival enlargement may be hereditary or acquired. Hereditary gingival fibromatosis is a rare form of gingival enlargement that effects the mandible and maxilla and is characterized by gingiva that grows slowly and progressively over a period of time. Excessive accumulation of extracellular matrix components seems to play a role in the pathogenesis of the gingival fibromatosis; however, the biochemical and mol.. Read More»