Abhishek Dhawan

Department of Community Medicine, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India

Publications

  • Review Article   
    G6PD Insufficiency, Redox Equilibrium, and Viral Infections: Insinuations for SARS-CoV-2
    Author(s): Abhishek Dhawan* and Swarupa Chakole

    The COVID-19 epidemic has inflicted damage on more than 4 crore 50 lakh people worldwide, resulting in over 10 lakh deaths. Infestation with the pathogenic SARS-CoV-2 virus leads to excessive inflammation and a cytokine storm, which leads to cell rupture due to a redox imbalance. The severe type of pneumonia caused by the human coronavirus (hCoV)-SARS-CoV-2 has caused heavy casualties, especially among the old age and those with comorbid illnesses all-inclusive of their age. The high mortality in African-American males, in general, raises the concern for a possible X-linked modulated process that could affect the viral pathogenesis and the immune system. When exposed to oxidants or infection, patients who lack the enzyme Glucose-6-Phosphate Dehydrogenase (G6PD) may have a haemolysis phenomenon. People with a G6PD deficiency are more prone to take up a virus than people with normal G6PD. .. Read More»

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