Abdulrahman M Alkassar Alanazi
Department of Forensic Medicine and Toxicology, Prince Sattam Ibn Abdelaziz University, Saudi Arabia Alkharj, KSAPublications
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Research
Effect of Some Nutritional Supplement on the Cerebellum against Cyclophosphamide Toxicity
Author(s): Ali Hassan A Ali*, Shaban Ragab Ibrahim, Abdulrahman M Alkassar Alanazi, Hamad Mesfer H Alatif, Abdulrahman M Almalki, Bandar Suliman S Alsultan, Bakheet Mulfi S Alrashdi and Yousef K Alhuzaimi
The cerebellum is the largest part of the hindbrain. As an important part of nervous system, it can be affected by oxidative stress. Dietary supplements had been proved that they have antioxidants properties that may protect our bodies against the effects of free radicals. One of these supplements is Aphanizomenon flos-aquae (AFA) that has health-improving effects especially on the nervous system. Cyclophosphamide (CP) is a widely used medication in chemotherapy and can cause oxidative stress. This study was conducted to investigate the role of AFA in preventing cyclophosphamide-induced adverse effects on the cerebellum of treated rats with CP. It is an experimental study carried out in the period from January 2021 to August 2021. It was carried out on 36 rats with body weights of 270-300 g. The animals were divided into three groups. The first is control group, the second one is CP t.. Read More»