Serum Calcium and Vitamin D Levels in Type 2 Diabetes Mellitus

Kanchana R^*

^*Correspondence: Kanchana R, Department of Physiology, Sree Balaji Medical College & Hospital Affiliated to Bharath Institute of Higher Education and Research, India, Email:

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Introduction

Pathogenesis of T2DM diabetes is involves the interaction of genetic and environmental factors. People with T2DM are reported to have many abnormalities. Hence there is a necessity to identify modifiable risk factors. Evidences from the previous studies say that calcium and vitamin D are such factors, when modified may control the diseases. Hence this study was done to estimate the serum calcium and vitamin D levels in T2DM and compare the values with non-diabetic samples [1-5].

Methodology

Results

Figure 1 shows the HbAl c, Plasma blood glucose levels, serum calcium, and vitamin D values among Diabetics and Non Diabetics. A p value of <0.01 was considered to be highly significant and was obtained for all parameters. A negative trend was seen between HbAlc and serum calcium in non-diabetics and between plasma blood glucose levels and vitamin D in non-diabetics. A positive trend was seen between plasma blood glucose levels and serum calcium in non-diabetics and also between vitamin D and serum calcium in none. From the results it was confirmed that a negative correlation was seen between plasma blood glucose levels and vitamin D in diabetics.

Figure 1: Blood parameters level.

Discussion and Conclusion

A negative correlation was seen between serum calcium, vitamin D levels and plasma blood glucose levels. A mcrease in plasma blood glucose levels was associated with decrease in serum calcium and vitamin D levels. Various studies had proved that vitamin D deficiency impairs the glucose mediated insulin secretion in our body. But the condition is restored when its supplemented. In this study A negative correlation was seen among serum calcium, vitamin D levels and HbA1c that is low serum calcium and vitamin D levels was associated with higher HbA1c [6-10].

Hence it was concluded from the study that supplementation of calcium along with vitamin D can prove to be a very cost effective and effective measure to control blood glucose levels in diabetics along with other measures such as exercise and oral hypoglycaemic.

References

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