Subclinical Hypothyroidism and High Sensitive C-Reactive Protein as Risk Markers for Coronary Artery Disease
Author(s): M Dilip Kumar*
Abstract
There is also a significant increase in the levels of Total Cholesterol (TC), Triglycerides (TGL), Low-Density Lipoproteins (LDL), and a decrease in High-Density Lipoprotein (HDL) levels. The study group consisted of 45 cases and age and sex matched controls (n=45) with 25 males and 20 females in each group. When the physical parameters were compared between the two groups, there was not much of difference in age, height and weight; however we observed a statistically significant difference in the BMI among the cases and controls. It was also observed that almost 9% of the subjects in the control group had TSH levels >4.5µ1U/mL 59 while almost 24 % of the cases had TSH values >4.5 µIU/mL (table 4 and figure 10 & 11), implying that 9% of the controls and 24% of the cases have Sub Clinical Hypothyroidism, even though the average TSH values between the cases and controls are not statistically significant. a significant increase in the levels of hs-CRP among the cases. When TSH levels were correlated with that of hs-CRP levels, we observed that a strong positive correlation exists between the two parameters in cases.