Stem Cell Regeneration in Endodontics
Author(s): Vedant Dhatrak*, Anuja Ikhar, Rushikesh Bhonde and Nutan Dhamdhere
Abstract
One of the most difficult tasks in modern dentistry is preserving important dental pulp with its associated vascular and nerve components. Mesenchymal Stem Cell (MSC) transplantation has shown the rising promise in regenerative medicine and dental translational practice due to its enormous potential for neovascularization. Powdery mesenchymal stem cells, which include postnatal dental pulp stem cells (from permanent teeth) and human exfoliated deciduous tuff stem cells, have distinct traits according to their neural crest or glial cell origins. The former involves exogenously injected stem cells, difficult procedures, and high expenses; the latter relies on the host's own cells to repair and regenerate tissue. This functional pulp regeneration provides a unique and promising method for future regenerative endodontics.