Potentials Compounds from Marine Invertebrates against Gram Negative Multi Drug Resistant (MDR) Pathogens
Author(s): MD Nadeem Bari*, Kuppannan Gobianand, Malarvizhi Arthanari, MD Rizwan Ansari and Imran Mohammad
Abstract
Globally, the occurrences of multi-drug resistant gram-negative bacteria have been created an imperative crisis. These bacteria have the restricted treatment preference resulting serious human health threats. Therefore, there is a need for searching an alternative measure should be taken against multidrug resistant bacteria immediately. Consequently, in this review, we focused on the marine antibacterial compounds which are documented from marine invertebrates like sponges, corals, bryozoans and tunicates with potent activity against these drug resistant bacteria were investigated. Marine network is a known as well as significant ecological niche for the discovery of promising bioactive compounds (peptides, macrocyles, terpenes, alkaloids, quinines etc.,) along with strong antibacterial potency against these resistant bacteria. This triggered us to review the marine bioactive compounds with excellent potency to fight against multi drug resistant bacteria.