Odontogenic Myxofibroma of the Jaw: A case report.
Author(s): Amir Alagib, Ashraf Deyab*, Reem H Wahbi and Mohammed Abdelnasir
Abstract
Odontogenic Myxofibroma is one of the comparatively rare benign mesenchymal odontogenic tumors in the jaw with a high recurrence rate. A 28-year-old female patient reported frequent pain for over one year. Extra-oral examination and Intra-oral examination were insignificant. Orthopantomography (OPG) showed a radiolucent lesion in the left canine and premolar region. Computed tomography scan reveals a well-defined reveal radiolucent cystic cavity lesion with an intact outer border of the mandible, and resorb of the lingual cortex. An excisional biopsy was performed and multiple irregular small pieces of soft tissue were enucleated and excised. The histopathological assessment revealed loose fibromxyomatous tumors exhibit a proliferation of spindle-shaped cells that produced wide mucoid-rich intercellular stroma(myxoid areas), consistent with Odontogenic Myxofibroma. Immunohistochemistry plays a great role in confirming and ruling out other differential diagnoses. The choice of treatment depends on certain variables such as localization, presence of a primary or recurrent lesion, age, general medical conditions, and aesthetic needs of the patient. The best management strategy applied in this patient is total enucleation of the lesion along with curettage of the cavity..