Nanomaterials and Nanotechnology in Brain Health
Author(s): Abdul Razak Mohamed Sikkander*
Abstract
As they are nanoparticles with a zero dimension, they can be divided into three classes: organic, inorganic and composite. The different physico-chemical characteristics of nanoparticles make them useful in many areas including medicine, pharmaceuticals and the food industry. However, having standardized toxicological studies is very important due to their ability to prevent the occurrence of neurotoxic effects although at the same time improving diagnosis and treatment of brain diseases. The main aim of this article is to shed light upon pros and cons associated with using nanoparticles for brain health. Given the growing number of medical products that are incorporating silver nanoparticles, consumer safety has now become a priority. Nanoparticles can be produced using three techniques; these include chemical, physical or biological methods. The final method is theoretically safe; the first two however entail various health risks. We therefore sought to examine histological alterations in the cerebellum of neonates. Each nanoparticle type has unique characteristics which are associated with different routes. The nanoparticles cannot cross into the brain without these checks. One such route which is bypassed by its own barriers is through blood-brain barrier as direct sensory nerves to brain. These nanoparticles impair sensory neurons and receptors making central nervous system neurotoxic.