KIDNEY INJURY IN INFLAMMATORY OWEL DISEASE
Author(s): Devang J Barad* and P Anandan
Abstract
IBD (Inflammatory Bowel Disease) is often associated with several extra-intestinal manifestations, involving various organ systems. It is estimated to be occurring in around 6-47% of IBD patients. Out of these, renal manifestations has an incidence of 4-23%. Simultaneously, conservative management of IBD requires a combination of drugs, including 5-ASAs (5-Aminosalicylates), steroids, antibiotics, immunosuppressive & biologic agents and, it is a known fact that these drugs, namely, 5-ASAs, few immunosuppressant & few biologic agents have known nephrotoxicity. So, in this way, patients of IBD, on treatment, are more prone for kidney injury – either as a part of primary disease process, or as a complication of drug therapy, or both. Here, we present a case of a 55 years old male with ulcerative colitis for 12 years, admitted with us for acute nephritic syndrome with acute kidney injury (AKI), which was thought to be drug-induced or secondary to both disease-process as well as drug-toxicity.