Efficacy of various hemostatic agents in controlling bleeding during dental procedures. A systematic review
Author(s): Marwa Salman Al Awad, Hanan Ahmed Alghamdi, Hend Abdrahman Ahmad, Khadijah Ali Almomen, Leena Faisal Al Jaafar and Suhael Ahmed*
Abstract
One of the common complications that occur in patients with hemostatic disorders after oral surgery is excessive bleeding. This study systematically reviews the available literature on evaluating the efficacy of various hemostatic agents used in dentistry in different dental procedures. This systematic review was done following the criteria of Cochrane Handbook for Systematic Reviews of Interventions Handbook. Authors also followed the recommendations of Preferred Reporting Items for Systematic Reviews and Metaanalysis (PRISMA) to conduct this systematic review. Various hemostatic agents have been investigated to accomplish hemostasis by the different mechanisms to limit bleeding and encourage coagulation. Studies confirmed that application of pressure with gauze containing tranexamic acid would be the management of choice. Chitosan proved superiority compared to Platelet Rich Fibrin in achieving hemostasis. Feracrylum and HemCon Dental Dressing have also resulted in positive association with coagulation especially in patients undergoing antiplatelet therapy. Haemocoagulase was correlated with paediatric patients, while Ankaferd Blood Stopper in hemophilic patients in hemostasis. Further studies are needed to support results.