Association Between Prolonged QTc Interval and Microalbuminuria in Patients of Type II Diabetes Mellitus
Author(s): S Sakthi Selva Kumar, S Palaniandavan and V Padma*
Abstract
Objectives: This study was done to find the association between QTc interval prolongation and microalbuminuria in patients of type II diabetes mellitus.
Methods: This cross-sectional study was conducted in SREE BALAJI MEDICAL COLLEGE AND HOSPITAL with 60patients of type 2 diabetes mellitus. A complete History and thorough clinical examination were recorded in these patients at the time of admission.
Results: Most of the patients were in 50 to 70 years of age group. There is a significant association between QTc interval prolongation and microalbuminuria as evidenced by a greater number of cases with microalbuminuria having prolonged QTc interval (67.76% Vs 24.13%, P<0.0001). Male to female ratio is 1.15:1.
Conclusion: There was a significant association between cardiac autonomic neuropathy (i.e. QTc interval prolongation) and microalbuminuria. Microalbuminuria doesn’t directly cause QTc interval prolongation, but it can be used as an indicator for patients who are prone to develop cardiac autonomic neuropathy and hence are at higher risk of having fatal arrhythmias.