A Case Report of Rodenticide Poisoning with Acute Kidney Injury.
Author(s): Preethi CD*, Anuradha N, Viknesh prabhu, Konda sanjith and Nethaji shree vaishnavi
Abstract
Rodenticide is widely used around the word. It contains various toxic components such as zinc or aluminum phosphide, yellow phosphorus, arsenic, thallium, sodium monofluroacetate. Rodenticide is easily available. Toxic effects may be produced by inhalation or ingestion. It may be accidental or intentional. The rodenticide in this case contains 38 percent zinc phosphide. Zinc phosphide produces phosphine gas when hydrolyzed by gastric acid. Phosphine gas is highly toxic. It produces toxicity within 30 minutes. It may produce symptoms such as nausea, vomiting, abdominal pain, hematemesis, arrhythmias, acute respiratory syndrome, respiratory failure, cardiac failure, liver failure and renal failure. Phosphine gas is highly toxic to respiratory system it inhibits cytochrome C oxidase. Poisoning from metal phosphide is prevalent, particularly in tropical nations. Through the phosphine gas-mediated effects on cellular respiration, aluminum and zinc phosphide poisoning have harmful effects. Majority of deaths are due to acute pulmonary edema, metabolic acidosis or distal renal tubular acidosis.